James M Cook Selected Research

Alprazolam (Xanax)

11/2021	Tolerance and dependence following chronic alprazolam treatment in rhesus monkeys: Role of GABAA receptor subtypes.
1/2018	Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABAA Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys.
8/2006	Enhanced sucrose pellet consumption induced by benzodiazepine-type drugs in squirrel monkeys: role of GABAA receptor subtypes.

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James M Cook Research Topics

Disease

13	Asthma (Bronchial Asthma) 02/2022 - 01/2016
12	Ataxia (Dyssynergia) 01/2022 - 06/2005
9	Pain (Aches) 06/2021 - 03/2011
9	Neoplasms (Cancer) 01/2021 - 04/2002
6	Inflammation (Inflammations) 01/2022 - 11/2013
6	Infections 11/2019 - 03/2009
6	Schizophrenia (Dementia Praecox) 01/2018 - 08/2011
5	Seizures (Absence Seizure) 04/2022 - 04/2014
5	Respiratory Hypersensitivity 02/2022 - 01/2016
5	Epilepsy (Aura) 01/2022 - 10/2018
5	Alcoholism (Alcohol Abuse) 01/2017 - 12/2003
4	Pneumonia (Pneumonitis) 02/2022 - 01/2020
3	Neuralgia (Stump Neuralgia) 01/2022 - 03/2011
3	Post-Traumatic Epilepsy (Epilepsy, Post Traumatic) 01/2022 - 01/2020
3	Cognitive Dysfunction 01/2021 - 01/2015
3	Medulloblastoma 05/2019 - 04/2014
2	Mental Disorders (Mental Disorder) 01/2022 - 04/2019
2	Autistic Disorder (Autism) 01/2022 - 11/2016
2	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 12/2020
2	Chronic Pain 01/2022 - 03/2011
2	Postpartum Depression (Post-Natal Depression) 01/2022 - 01/2022
2	Hyperalgesia 06/2021 - 03/2014
2	Shock 01/2021 - 12/2010
2	Bronchial Spasm 12/2020 - 01/2012
2	Sleep Initiation and Maintenance Disorders (Insomnia) 07/2017 - 05/2002
2	Alzheimer Disease (Alzheimer's Disease) 11/2016 - 10/2009
2	Melioidosis 01/2012 - 01/2012
2	Breast Neoplasms (Breast Cancer) 04/2008 - 12/2006
2	Carcinoma (Carcinomatosis) 04/2008 - 04/2002
1	Neuroinflammatory Diseases 11/2022
1	Brain Injuries (Brain Injury) 01/2022
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2022
1	Tinnitus 01/2022
1	Tremor (Tremors) 01/2022
1	Drug Resistant Epilepsy 01/2022
1	Anxiety Disorders (Anxiety Disorder) 01/2021
1	Melanoma (Melanoma, Malignant) 01/2021

Drug/Important Bio-Agent (IBA)

15	Pharmaceutical PreparationsIBA 02/2022 - 03/2011
13	LigandsIBA 11/2022 - 02/2004
12	BenzodiazepinesIBA 01/2022 - 05/2002
11	gamma-Aminobutyric Acid (GABA)IBA 01/2022 - 12/2003
10	GABA-A Receptors (GABA(A) Receptor)IBA 01/2021 - 05/2002
8	Aminobutyrates (Aminobutyric Acid)IBA 01/2022 - 01/2015
8	Diazepam (Valium)FDA LinkGeneric 01/2022 - 06/2009
8	MIDD0301IBA 01/2022 - 01/2018
5	KRM-II-81IBA 04/2022 - 01/2017
5	Anti-Anxiety Agents (Anxiolytics)IBA 01/2021 - 12/2010
5	Zolpidem (Ambien)FDA LinkGeneric 01/2018 - 03/2005
4	OvalbuminIBA 12/2020 - 01/2016
4	Biological ProductsIBA 01/2020 - 04/2002
4	Anticonvulsants (Antiepileptic Drugs)IBA 01/2020 - 11/2013
4	Hypnotics and Sedatives (Sedatives)IBA 01/2020 - 03/2011
3	LipopolysaccharidesIBA 02/2022 - 12/2020
3	Midazolam (Versed)FDA LinkGeneric 11/2021 - 03/2005
3	Alprazolam (Xanax)FDA LinkGeneric 11/2021 - 08/2006
3	Dopamine (Intropin)FDA LinkGeneric 01/2015 - 08/2011
3	Anti-Bacterial Agents (Antibiotics)IBA 02/2012 - 01/2012
2	Pentylenetetrazole (Metrazol)IBA 04/2022 - 05/2014
2	SteroidsIBA 02/2022 - 12/2020
2	Albuterol (Salbutamol)FDA LinkGeneric 02/2022 - 12/2020
2	NeurosteroidsIBA 01/2022 - 01/2022
2	SH-053-2'F-R-CH3IBA 01/2022 - 01/2015
2	AnionsIBA 01/2021 - 05/2019
2	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 01/2021 - 04/2014
2	ChloridesIBA 01/2021 - 05/2019
2	Methacholine Chloride (Methacholine)FDA Link 12/2020 - 01/2017
2	Small Interfering RNA (siRNA)IBA 01/2019 - 04/2014
2	ZymosanIBA 01/2017 - 03/2011
2	Carbolines (Beta-Carbolines)IBA 11/2015 - 11/2010
2	PS121912IBA 11/2015 - 10/2014
2	Amphetamine (Amfetamine)FDA LinkGeneric 09/2015 - 01/2015
2	Methylazoxymethanol AcetateIBA 03/2014 - 08/2011
2	Ceftazidime (Fortum)FDA LinkGeneric 01/2012 - 01/2012
2	Mitochondrial DNA (mtDNA)IBA 04/2011 - 03/2009
2	Proteins (Proteins, Gene)FDA Link 04/2008 - 12/2006
2	Etoposide (VP 16)FDA LinkGeneric 04/2008 - 04/2002
1	Amyloid beta-PeptidesIBA 11/2022
1	InterferonsIBA 01/2022
1	HalogensIBA 01/2022
1	brexanoloneIBA 01/2022
1	Valproic Acid (Depakote)FDA LinkGeneric 01/2022
1	Morphine (MS Contin)FDA LinkGeneric 06/2021
1	Opioid Analgesics (Opioids)IBA 06/2021
1	Opioid Receptors (Opioid Receptor)IBA 06/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	Antidepressive Agents (Antidepressants)IBA 01/2021
1	Freund's AdjuvantIBA 01/2021
1	CytokinesIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Dimenhydrinate (DMH)FDA LinkGeneric 01/2021
1	SK&F 82958 (SKF 82958)IBA 01/2021
1	CorticosteroneIBA 01/2021
1	Triazolam (Halcion)FDA LinkGeneric 01/2021

Therapy/Procedure

8	Therapeutics 01/2022 - 01/2012
3	Deep Sedation 11/2021 - 01/2018
2	Oral Administration 01/2022 - 01/2018
2	Self Administration (Administration, Self) 11/2015 - 03/2004
2	Drug Therapy (Chemotherapy) 04/2014 - 01/2012
1	Radiotherapy 01/2021
1	Immunotherapy 01/2021